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Glucophage should be taken with meals. Metformin increases the sensitivity of muscle cells to insulin. Metformin can rarely cause a serious condition called lactic acidosis. Your liver makes and that your stomach absorbs. Take by mouth. Glucophage tablets contain the active ingredient Metformin hydrochloride. Metformin works by helping to restore your body's proper response to the insulin you naturally produce, and by decreasing the amount of glucose you absorb from your food and the amount of glucose made by your liver. People who are overweight.
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