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As long as your doctor advises. It is important to take Paxil and talk to your doctor if you experience headache nervousness, or anxiety nausea, diarrhea, or changes in appetite or weight. Depression and anxiety disorders usually require long-term treatment because of their chronic nature and the risk of relapse. The first and only medication in the class of antidepressants known as selective serotonin reuptake inhibitors. Social anxiety disorder and generalized anxiety disorder. It could take several weeks before you start feeling better. Paxil is well established in treating depression after nearly ten years and over ten million patient treatments. It may take one month or more for you to start feeling better and unpleasant side effects may be experienced if you stop taking Paroxetine. As often as several times a week or even per day, causing significant distress.